Lazebnik L B, Vertkin A L, Malichenko S B, Li E D, Konev Iu V, Romanovskaia T V, Goncharov L F
Klin Med (Mosk). 1996;74(3):29-33.
Cardiovascular disease is the principal cause of morbidity, functional disability and fatal outcomes in patients with non-insulin-dependent diabetes mellitus (NIDDM). The results of administration of eikonol, food additive containing omega-3 unsaturated fatty acids, for 3 months were analyzed for 60 elderly NIDDM patients with ischemic heart disease. A single administration of eikonol leads to a decrease in accumulation of intracellular cholesterol by 15%. Diet eikonol decreased the level of total cholesterol and triglycerides in the blood by 23 and 43%, respectively. Moreover, the higher is the initial value of these parameters, the higher is the effect of the preparation. Eikonol proved to increase the level of lipoproteins of high density, produced a positive trends in NIDDM clinical picture. Food additive eikonol is recommended for wide administration in elderly NIDDM patients with atherogenic dyslipidemias.
心血管疾病是非胰岛素依赖型糖尿病（NIDDM）患者发病、功能残疾和致命后果的主要原因。对60例患有缺血性心脏病的老年NIDDM患者分析了服用含有ω-3不饱和脂肪酸的食品添加剂茶多酚3个月的结果。单次服用茶多酚可使细胞内胆固醇积累减少15%。饮食中添加茶多酚分别使血液中总胆固醇和甘油三酯水平降低23%和43%。此外，这些参数的初始值越高，该制剂的效果就越明显。茶多酚被证明可提高高密度脂蛋白水平，在NIDDM临床症状方面产生了积极趋势。建议在患有致动脉粥样硬化血脂异常的老年NIDDM患者中广泛使用食品添加剂茶多酚。
