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[使用益康宁(一种不饱和脂肪酸复合物)治疗非胰岛素依赖型糖尿病的经验]

[Experience in the use of eiconol (a complex of unsaturated fatty acids) in non-insulin-dependent diabetes mellitus].

作者信息

Lazebnik L B, Vertkin A L, Malichenko S B, Li E D, Konev Iu V, Romanovskaia T V, Goncharov L F

出版信息

Klin Med (Mosk). 1996;74(3):29-33.

PMID:8926697
Abstract

Cardiovascular disease is the principal cause of morbidity, functional disability and fatal outcomes in patients with non-insulin-dependent diabetes mellitus (NIDDM). The results of administration of eikonol, food additive containing omega-3 unsaturated fatty acids, for 3 months were analyzed for 60 elderly NIDDM patients with ischemic heart disease. A single administration of eikonol leads to a decrease in accumulation of intracellular cholesterol by 15%. Diet eikonol decreased the level of total cholesterol and triglycerides in the blood by 23 and 43%, respectively. Moreover, the higher is the initial value of these parameters, the higher is the effect of the preparation. Eikonol proved to increase the level of lipoproteins of high density, produced a positive trends in NIDDM clinical picture. Food additive eikonol is recommended for wide administration in elderly NIDDM patients with atherogenic dyslipidemias.

摘要

心血管疾病是非胰岛素依赖型糖尿病(NIDDM)患者发病、功能残疾和致命后果的主要原因。对60例患有缺血性心脏病的老年NIDDM患者分析了服用含有ω-3不饱和脂肪酸的食品添加剂茶多酚3个月的结果。单次服用茶多酚可使细胞内胆固醇积累减少15%。饮食中添加茶多酚分别使血液中总胆固醇和甘油三酯水平降低23%和43%。此外,这些参数的初始值越高,该制剂的效果就越明显。茶多酚被证明可提高高密度脂蛋白水平,在NIDDM临床症状方面产生了积极趋势。建议在患有致动脉粥样硬化血脂异常的老年NIDDM患者中广泛使用食品添加剂茶多酚。

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