Malichenko S B, Lazebnik L B, Vertkin A L, Konev Iu V, Romanovskaia T V, Smirnova O I
Ter Arkh. 1996;68(10):15-8.
A nutritional additive eikonol containing polyunsaturated fatty acids omega-3 was given for a month (8 g/day) to correct vascular complications in 60 patients with non-insulin-dependent diabetes mellitus (NIDDM). Eikonol-treated NIDDM patients with diabetic retinopathy, polyneuropathy, angiopathy of the legs combining with arterial hypertension exhibited a reduction in the levels of total cholesterol, triglycerides, low and very low density lipoproteins cholesterol, a rise in concentrations of high density lipoproteins cholesterol. Blood pressure went down, peripheral vascular resistance and microhemocirculation improved. The findings evidence prophylactic and therapeutic efficacy of eikonol in vascular complications of NIDDM.
给60例非胰岛素依赖型糖尿病（NIDDM）患者服用一种含有多不饱和脂肪酸ω-3的营养添加剂——鲨肝醇，为期一个月（8克/天），以纠正血管并发症。接受鲨肝醇治疗的患有糖尿病视网膜病变、多发性神经病变、腿部血管病变合并动脉高血压的NIDDM患者，其总胆固醇、甘油三酯、低密度和极低密度脂蛋白胆固醇水平降低，高密度脂蛋白胆固醇浓度升高。血压下降，外周血管阻力和微循环得到改善。这些发现证明了鲨肝醇对NIDDM血管并发症的预防和治疗效果。
