Rubini P, Bonati L, Japichino G G
Istituto di Clinica Chirurgica Generale, Università degli Studi, Parma.
Minerva Chir. 1996 Apr;51(4):195-201.
The authors report their experience in the management of 54 patients who underwent emergency surgery for rupture of an abdominal aortic aneurysm, correlating results to time of diagnosis. The overall mortality rate was 55.5%. The extent and the site of bleeding, free blood in peritoneal cavity or retroperitoneal hematoma alone, were critical factors influencing survival and were correlated to early of diagnosis. Patients with small hematomas had no mortality; cases with more extensive hematomas had a mortality rate of 53%; in case of intraperitoneal bleeding the mortality rose to 73% (p = 0.001). The median times between symptoms' onset and surgical intervention was correlated with a significant value to extent of retroperitoneal hematoma (p = 0.003). This time is also significantly different in dead patients compared to survivors (p < 0.001). In patients with incorrect admitting diagnosis the mean times between onset of symptoms and surgical treatment was significantly different from time of correctly diagnosed patients (p < 0.001). Our findings emphasize the need for rapid recognition of prodromal symptoms of rupture and the earlier referral of patients with known abdominal aneurysm; we suggest that in an unstable patient with a suspected ruptured aneurysm immediate surgery should be performed without delay for confirmatory tests or full resuscitation.
作者报告了他们对54例因腹主动脉瘤破裂而接受急诊手术患者的治疗经验,并将结果与诊断时间相关联。总体死亡率为55.5%。出血的范围和部位,即仅腹腔内游离血或腹膜后血肿,是影响生存的关键因素,且与诊断的及时性相关。小血肿患者无死亡;血肿范围较大的患者死亡率为53%;腹腔内出血时死亡率升至73%(p = 0.001)。症状出现至手术干预的中位时间与腹膜后血肿范围具有显著相关性(p = 0.003)。与存活患者相比,死亡患者的这一时间也有显著差异(p < 0.001)。在入院诊断错误的患者中,症状出现至手术治疗的平均时间与诊断正确的患者有显著差异(p < 0.001)。我们的研究结果强调了快速识别破裂前驱症状以及对已知腹主动脉瘤患者更早转诊的必要性;我们建议,对于疑似动脉瘤破裂的不稳定患者,应立即进行手术,无需等待确诊检查或充分复苏。