Kannisto M, Rintala R
Children's Hospital, University of Helsinki, Finland.
Paraplegia. 1995 Dec;33(12):701-3. doi: 10.1038/sc.1995.147.
The impact of neuropathic bowel dysfunction on bowel habits was studied in 35 adult spinal cord injury (SCI) patients, who had sustained their injury in childhood. The methods used in the study were clinical interview and examination, quantitative scoring of bowel function (BCS) and estimation of bowel transit time with radiopaque markers. Thirty five healthy subjects without previous anorectal disease or surgery and with similar age and sex distribution as the patients served as controls. Most of the SCI patients were content with their bowel function. Nine (26%) out of 35 of the SCI patients were completely satisfied with their bowel function and reported no limitations in social life. The majority (69%) of the patients considered their bowel function to be significantly altered, causing only mild problems in their social life. Two of the patients had major problems of bowel function, which caused severe limitations in their social life. The majority (77%) of the patients declared that they had a low frequency of bowel evacuation. Eight out of 35 patients were using laxatives to promote bowel emptying. The quantitative BCS of the patients was significantly lower than that of the controls (P < 0.001). Moreover, there was a significant difference between the scores of patients with complete high (C2-T6) and complete low (T7-S4-5) lesions. The difference between the BCS and overall satisfaction with bowel function can be explained by good habilitation to SCI and by the prolonged transit times which enables relatively rare and controlled bowel movements and firm consistency of stools.
对35名童年期遭受脊髓损伤（SCI）的成年患者的神经性肠道功能障碍对排便习惯的影响进行了研究。该研究采用的方法包括临床访谈和检查、肠道功能定量评分（BCS）以及使用不透射线标志物估计肠道运输时间。35名无既往肛肠疾病或手术史、年龄和性别分布与患者相似的健康受试者作为对照。大多数SCI患者对其肠道功能感到满意。35名SCI患者中有9名（26%）对其肠道功能完全满意，且报告在社交生活中没有限制。大多数患者（69%）认为其肠道功能有显著改变，仅在社交生活中引起轻微问题。其中两名患者存在严重的肠道功能问题，在社交生活中造成严重限制。大多数患者（77%）宣称他们的排便频率较低。35名患者中有8名使用泻药促进排便。患者的定量BCS显著低于对照组（P < 0.001）。此外，完全高位（C2 - T6）和完全低位（T7 - S4 - 5）损伤患者的评分之间存在显著差异。BCS与肠道功能总体满意度之间的差异可以通过对SCI的良好康复以及较长的运输时间来解释，较长的运输时间使得排便相对较少且可控，粪便质地坚硬。
