Fourtassi M, Charvier K, Hajjioui A, Havé L, Rode G
Service de neuropérinéologie et sexologie, hôpital Henry-Gabrielle, hospices civil de Lyon, 20, route de Vourles, 69230 Saint-Genis-Laval, France.
Prog Urol. 2012 Jul;22(8):467-74. doi: 10.1016/j.purol.2012.04.010. Epub 2012 May 30.
Bowel dysfunction and disordered defecation are very common after spinal cord injury (SCI) and can have a major impact on patients' social life and quality of life. The aim of this study was to assess the safety and efficacy of transanal irrigations (TAI) in the management of Bowel dysfunction in SCI patients.
Forty-five consecutive SCI patients using TAI were retrospectively included. TAI efficacy was assessed through Neurogenic Bowel Dysfunction (NBD) score recorded before and after 8 weeks of regular use. Possible side effects were assessed with a semi-structured questionnaire. Patients who started TAI use at least 6 months previously were contacted to assess long-term compliance, efficacy and safety of TAI.
After 8 weeks of regular use of TAI, the average NBD scores decreased by four points (P<0.0001) with a specific improvement in the items related to stool frequency (P: 0.036), occurrence of malaise, headache, or sweating during defecation (P: 0.043), use of drugs against constipation (P: 0.007) and frequency of fecal incontinence (P: 0.001). The main side effects were bleeding (10%) and abdominal pain (8%). At 6 months, 80% of the assessed patients had continued regular use of TAI with no particular problem.
This study showed good medium and long-term efficacy and safety of TAI in the management of bowel dysfunction and defecation disorders in spinal cord-injured patients.
肠道功能障碍和排便紊乱在脊髓损伤(SCI)后非常常见,会对患者的社交生活和生活质量产生重大影响。本研究的目的是评估经肛门灌洗(TAI)在脊髓损伤患者肠道功能障碍管理中的安全性和有效性。
回顾性纳入45例连续使用TAI的脊髓损伤患者。通过在规律使用8周前后记录的神经源性肠道功能障碍(NBD)评分来评估TAI的疗效。使用半结构化问卷评估可能的副作用。联系至少在6个月前开始使用TAI的患者,以评估TAI的长期依从性、疗效和安全性。
在规律使用TAI 8周后,平均NBD评分下降了4分(P<0.0001),与排便频率(P:0.036)、排便时不适、头痛或出汗的发生率(P:0.043)、使用抗便秘药物(P:0.007)以及大便失禁频率(P:0.001)相关的项目有明显改善。主要副作用为出血(10%)和腹痛(8%)。在6个月时,80%接受评估的患者继续规律使用TAI,没有特别问题。
本研究表明TAI在脊髓损伤患者肠道功能障碍和排便紊乱的管理中具有良好的中长期疗效和安全性。