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[Interferon alpha in the treatment of polycythemia vera in a 13-year-old girl].

作者信息

Ołpiński M, Jakieła T, Korczowski R

机构信息

Oddział Dzieciecy Szpitala Wojewódzkiego nr 2 w Rzeszowie.

出版信息

Pediatr Pol. 1996 Aug;71(8):705-7.

PMID:8927476
Abstract

The authors present a rare case of polycythemia vera (PV) in a 13-year-old girl initially treated with phlebotomy only and then also with interferon alpha at a dose of 3 x 10(6) U three times per week subcutaneously. The treatment outcome measure was the reduction of the number of phlebotomies required to retain a normal hematocrit value. Treatment with interferon enabled a substantial reduction of phlebotomies and caused a decrease in platelet count. These results confirm that interferon alpha may be regarded as a promising therapeutic approach in the management of PV.

摘要

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[Interferon alpha in the treatment of polycythemia vera in a 13-year-old girl].
Pediatr Pol. 1996 Aug;71(8):705-7.
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[Successful treatment with interferon-alpha in a case of acute myeloid leukemia with del (20q) following polycythemia vera].[真性红细胞增多症后伴del(20q)的急性髓系白血病患者应用α干扰素成功治疗]
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9
Quantitative real-time polymerase chain reaction shows that treatment with interferon reduces the initially upregulated PRV-1 expression in polycythemia vera patients.定量实时聚合酶链反应显示,干扰素治疗可降低真性红细胞增多症患者最初上调的PRV-1表达。
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