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[乳糜泻患儿的血清催乳素浓度]

[Serum prolactin concentration in children with celiac disease].

作者信息

Gocyła U, Szczepański Z, Kalita B, Sikora A, Slimok M

机构信息

III Katedra i Klinika Pediatrii Slaskiej Akademii Medyeznej w Bytomiu.

出版信息

Pediatr Pol. 1996 Sep;71(9):797-800.

PMID:8927488
Abstract

The study encompassed 62 children aged 4-15 years: 51 with a confirmed diagnosis of celiac disease and 11 suspected of having celiac disease (during diagnostic studies). The control group included 30 healthy children aged 4-15 years. Serum prolactin concentration was measured using radioimmunoassay (RIA) kits. Serum prolactin concentrations were significantly higher in children with celiac disease not following a gluten-free diet than in the control group. Children with serious mucosal lesions revealed by small bowel mucosal biopsies had the highest serum prolactin concentrations. Of these children, 36% gad values higher than 15 ng/ml. Differences between children with celiac disease complying with a gluten-free diet and the control group were not significant.

摘要

该研究纳入了62名4至15岁的儿童:51名确诊为乳糜泻,11名(在诊断研究期间)疑似患有乳糜泻。对照组包括30名4至15岁的健康儿童。使用放射免疫分析(RIA)试剂盒测量血清催乳素浓度。未遵循无麸质饮食的乳糜泻儿童的血清催乳素浓度显著高于对照组。经小肠黏膜活检显示有严重黏膜病变的儿童血清催乳素浓度最高。在这些儿童中,36%的值高于15 ng/ml。遵循无麸质饮食的乳糜泻儿童与对照组之间的差异不显著。

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