Gocyła U, Szczepański Z, Kalita B, Sikora A, Slimok M
III Katedra i Klinika Pediatrii Slaskiej Akademii Medyeznej w Bytomiu.
Pediatr Pol. 1996 Sep;71(9):797-800.
The study encompassed 62 children aged 4-15 years: 51 with a confirmed diagnosis of celiac disease and 11 suspected of having celiac disease (during diagnostic studies). The control group included 30 healthy children aged 4-15 years. Serum prolactin concentration was measured using radioimmunoassay (RIA) kits. Serum prolactin concentrations were significantly higher in children with celiac disease not following a gluten-free diet than in the control group. Children with serious mucosal lesions revealed by small bowel mucosal biopsies had the highest serum prolactin concentrations. Of these children, 36% gad values higher than 15 ng/ml. Differences between children with celiac disease complying with a gluten-free diet and the control group were not significant.
该研究纳入了62名4至15岁的儿童:51名确诊为乳糜泻,11名(在诊断研究期间)疑似患有乳糜泻。对照组包括30名4至15岁的健康儿童。使用放射免疫分析(RIA)试剂盒测量血清催乳素浓度。未遵循无麸质饮食的乳糜泻儿童的血清催乳素浓度显著高于对照组。经小肠黏膜活检显示有严重黏膜病变的儿童血清催乳素浓度最高。在这些儿童中,36%的值高于15 ng/ml。遵循无麸质饮食的乳糜泻儿童与对照组之间的差异不显著。