Szychowska Z, Gruszka J, Kuchar E
Klinika Chorób Zakaźnych Dzieci AM we Wrocławiu.
Przegl Epidemiol. 1996;50(3):273-9.
Two children with Kawasaki disease (KD), a girl 3 yrs. and a boy 2.5 yrs., were described. The children met all criteria for the diagnosis of KD (fever, conjunctivitis, oral changes, extremity changes, rash, lymphadenopathy), and other diseases were excluded. In both children or one of them other clinical and laboratory findings occasionally detected in KD were observed: arthralgia, hepatomegaly and splenomegaly, slight elevation of transaminases and bilirubin level, slight elevation of CSF pleocytosis, sterile pyuria and hematuria. Electrocardiograms revealed sinus tachycardia and transient disturbances of heart repolarization. In both children changes in blood morphology and biochemical disturbances typical for inflammatory processes were noted. Thrombocytosis was seen in the 2nd week of the illness in the child in whom platelet counts were controlled. The child in whom diagnosis of KD was established in the first week of symptoms was treated with acetylsalicylic acid along with an oral penicillin. A child with retrospectively diagnosed KD was treated with antibiotics and corticosteroids. Clinical and laboratory findings of KD resolved in both children within 4-6 weeks without complications from coronary blood vessels.
描述了两名川崎病（KD）患儿，一名3岁女孩和一名2.5岁男孩。这两名患儿均符合KD的所有诊断标准（发热、结膜炎、口腔改变、四肢改变、皮疹、淋巴结病），且排除了其他疾病。在两名患儿或其中一名患儿中，偶尔观察到KD中其他临床和实验室检查结果：关节痛、肝肿大和脾肿大、转氨酶和胆红素水平轻度升高、脑脊液细胞数轻度增多、无菌性脓尿和血尿。心电图显示窦性心动过速和心脏复极短暂异常。在两名患儿中均注意到血液形态学变化和炎症过程典型的生化紊乱。在对血小板计数进行监测的患儿中，在疾病第2周出现血小板增多。在症状出现第一周确诊为KD的患儿接受了阿司匹林和口服青霉素治疗。一名回顾性诊断为KD的患儿接受了抗生素和皮质类固醇治疗。两名患儿的KD临床和实验室检查结果在4至6周内均得到缓解，未出现冠状动脉并发症。
