Bermejo B, Olona M, Serra M, Carrera A, Vaqué J
Servicio de Medicina Preventiva y Epidemiología, Hospitals Vall d'Hebron, Barcelona.
Rev Clin Esp. 1996 Jul;196(7):446-50.
Iron deficiency is particularly common among women in child-bearing age. The early detection and institution of an appropriate therapy can prevent the development of anemia.
To study the prevalence of iron deficiency among women in child-bearing age (in the setting of periodic health visits) and the associated risk factors.
A cross-sectional observational study was undertaken with 322 women in child-bearing age. An hemogram and serum ferritin levels were obtained on the same day when an interview was carried out to obtain data on general personal details, gynecological-obstetrical antecedents, diet, sports, and blood donations. Iron deficiency was defined as a serum ferritin concentration lower than 25 ng/ml.
The prevalence of iron deficiency was 47.5%. In the multivariate analysis, factors significantly influencing on prevalence were: a copious menstruation blood loss (OR = 4.64, CI 2.22-9.68), a body mass index higher than 25 (OR = 0.49; CI 0.27-0.89) and maternity (OR = 2.08; CI 1.12-3.84). The likelihood associated with chi square goodness-of-fit was 0.08.
The prevalence of iron deficiency detected is high; although there are clear associated risk factors, the goodness-of-fit was poor; therefore, for predictive purposes it is not possible to delineate a group in a special risk for iron deficiency.
缺铁在育龄女性中尤为常见。早期发现并采取适当治疗可预防贫血的发生。
研究育龄女性(在定期健康检查中)缺铁的患病率及相关危险因素。
对322名育龄女性进行了一项横断面观察性研究。在进行访谈以获取一般个人信息、妇产科病史、饮食、运动和献血等数据的同一天,检测血常规和血清铁蛋白水平。缺铁定义为血清铁蛋白浓度低于25 ng/ml。
缺铁患病率为47.5%。多因素分析显示,对患病率有显著影响的因素包括:月经量过多(比值比=4.64,95%置信区间2.22 - 9.68)、体重指数高于25(比值比=0.49;95%置信区间0.27 - 0.89)和生育情况(比值比=2.08;95%置信区间1.12 - 3.84)。卡方拟合优度相关的可能性为0.08。
检测到的缺铁患病率较高;尽管存在明确的相关危险因素,但拟合优度较差;因此,出于预测目的,无法确定缺铁特别高危的人群。