Lacassagne L, Didier A, Murrisespin M, Rouquet R M, Clave D, Lemozy J, Giron J, Leophonte P
Service de Pneumologie-Allergologie, CHU Toulouse-Rangueil, Toulouse.
Rev Mal Respir. 1996;13(4):433-6.
Pulmonary nocardiosis is a respiratory infection which is usually described in the immunocompromised. We report three cases in patients suffering from chronic airflow obstruction. In two cases there was a parenchymal disorder and in one case bronchial suppuration without involvement of the alveolar region. The diagnosis was made in all cases by bacteriological examination from specimens obtained at fiberoptic bronchoscopy. The outcome was favourable in all three cases after appropriate treatment. These observations underline the diversity of the clinical forms of respiratory nocardiosis. Furthermore, it demonstrates their possible occurrence in non-immunocompromised patients and the need to look for this germ specifically in long drawn infections. A bacteriological diagnosis is vital to start early and appropriate antibiotic therapy which should be prolonged because of the risk of recurrence and disseminated infection.
肺诺卡菌病是一种通常在免疫功能低下者中描述的呼吸道感染。我们报告了3例慢性气流阻塞患者的病例。2例存在实质性病变，1例为支气管化脓，未累及肺泡区域。所有病例均通过纤维支气管镜检查获取的标本进行细菌学检查做出诊断。经过适当治疗，所有3例患者的预后均良好。这些观察结果强调了呼吸道诺卡菌病临床形式的多样性。此外，它表明其可能发生在非免疫功能低下的患者中，以及在长期感染中特别寻找这种病菌的必要性。细菌学诊断对于尽早开始适当的抗生素治疗至关重要，由于存在复发和播散性感染的风险，抗生素治疗应延长。
