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[急性血吸虫病或卡塔亚马综合征:关于两起小范围流行疫情]

[Acute schistosomiasis or Katayama syndrome: apropos of 2 mini-epidemics].

作者信息

Loutan L, Farinelli T, Robert C F

机构信息

Département de médicine communautaire, Hôpitaux universitaires de Genéve.

出版信息

Schweiz Med Wochenschr. 1996 Aug 31;126(35):1482-6.

PMID:8927951
Abstract

Schistosomiasis, or bilharziasis, is often oligosymptomatic but there is also an acute form, the Katayama syndrome. Observation of two groups of travelers who swam in the same lake near Banfora in western Burkina Faso, separated by an interval of one year, illustrates the high infection rate of Schistosoma mansoni (100% of swimmers, of whom 82% were symptomatic and 55% presented with fever). The incubation period was 4 to 6 weeks after exposure. 10 of the 11 subjects had eosinophilia (> or = 500/mm3) and IFAT serology was positive in all tested subjects. More than one year after exposure, one traveler (untreated) presented with a neurological deficit due to acute schistosomal myelitis. The diagnosis of schistosomiasis in a patient requires a search for the disease among his fellow travelers, even if they are asymptomatic.

摘要

血吸虫病,又称裂体吸虫病,通常症状不明显,但也有急性形式,即卡塔亚马综合征。对两组在布基纳法索西部班福拉附近同一湖泊游泳的旅行者进行观察,两组间隔一年,结果表明曼氏血吸虫感染率很高(游泳者感染率达100%,其中82%有症状,55%出现发热)。潜伏期为接触后4至6周。11名受试者中有10名嗜酸性粒细胞增多(≥500/mm³),所有检测受试者的间接荧光抗体试验血清学均呈阳性。接触一年多后,一名未接受治疗的旅行者因急性血吸虫性脊髓炎出现神经功能缺损。对一名患者进行血吸虫病诊断时,即使其同行者无症状,也需要在同行者中排查该病。

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