Granier H, Potard M, Diraison P, Nicolas X, Laborde J P, Talarmin F
Service de médecine interne et maladies infectieuses et tropicales, Hôpital d'Instruction des Armées Clermont Tonnerre, 29240 Brest Naval, France.
Med Trop (Mars). 2003;63(1):60-3.
A 24-year-old man returning from a trip to Mali was hospitalized for acute encephalitis and fever in association with acute primary infection by Schistosomiasis mansoni. Bilharziasis was suspected from the epidemiological context and presence of eosinophilia. Diagnosis was confirmed by serological testing. Specific treatment using praziquantel and corticotherapy was successful. Central nervous system involvement attributable to embolization of eggs or ectopic migration of adult worms has been reported in association with chronic Schistosomiasis by S. japonicum or S. mansoni. There have been few reports of acute neuroschistosomiais during the acute primary phase of infestation by S. mansoni. Etiology probably involves immunoallergic mechanisms.
一名从马里旅行归来的24岁男子因急性脑炎和发热住院，伴有曼氏血吸虫急性原发性感染。从流行病学背景和嗜酸性粒细胞增多症怀疑为血吸虫病。血清学检测确诊。使用吡喹酮和皮质激素疗法的特异性治疗取得成功。日本血吸虫或曼氏血吸虫引起的慢性血吸虫病与虫卵栓塞或成虫异位迁移导致的中枢神经系统受累已有报道。关于曼氏血吸虫急性感染初期急性神经血吸虫病的报道很少。病因可能涉及免疫过敏机制。
