Graff-Iversen S
Statens helseundersøkelser, Oslo.
Tidsskr Nor Laegeforen. 1996 Sep 20;116(22):2669-72.
In epidemiology and preventive medicine, absolute risk, relative risk and population attributable risk are well defined concepts. In research, the relative risks are of great interest, but to make medical decisions it is necessary to assess the risks and benefits in absolute rather than relative terms. Therefore, editors and referees should promote the presentation of absolute risks in medical journals. Critical comments on risk interventions are often of a general nature, and include all risk factors and all actual interventions. To assess the benefits, each disease, each risk, and each intervention has to be handled separately. In the prevention of cardiovascular diseases the effects of several interventions have been documented. The quality of the performance is of great importance, however, when interventions from clinical trials are applied in practical medicine.
在流行病学和预防医学中,绝对风险、相对风险和人群归因风险是定义明确的概念。在研究中,相对风险备受关注,但在做出医疗决策时,有必要从绝对而非相对的角度评估风险和益处。因此,编辑和审稿人应推动医学期刊呈现绝对风险。对风险干预的批判性评论通常较为笼统,涵盖所有风险因素和所有实际干预措施。为评估益处,每种疾病、每种风险和每种干预都必须分别处理。在心血管疾病的预防方面,已有多项干预措施的效果记录在案。然而,当将临床试验中的干预措施应用于实际医疗时,实施的质量至关重要。