Rickey D W, Fenster A
Imaging Research Laboratories, Robarts Research Institute, London, Ontario, Canada.
Ultrasound Med Biol. 1996;22(1):61-73. doi: 10.1016/0301-5629(95)02033-0.
An adaptive real-time Doppler peak-frequency tracing algorithm was evaluated in vitro and compared to manual peak-frequency traces. A computer-controlled pump was used to generate physiological flow waveforms in a vasculature-mimicking phantom. Spectral waveforms were obtained on an ATL HDI along with real-time estimates of diagnostic parameters, including maximum systolic, minimum diastolic, time-averaged peak frequencies and pulsatility and resistance indices. The effect of the signal-to-noise ratio on the measured parameters was investigated. The imprecision in the measured parameters was found to depend somewhat on the waveform shape; e.g., the imprecision in PI was 4.1% for a normal renal waveform and 8.5% for a waveform having reverse diastolic flow. The peak frequency envelopes of the same waveform data were traced manually by nine operators, and the resulting diagnostic parameters were compared to ones obtained from automated peak-frequency traces of the same waveform data. The agreement between parameters measured by the automated routine and those measured manually was found to depend somewhat on the waveform shape; e.g., the bias in the PI was 1.3% for a renal waveform lacking diastolic flow, and 12% for a waveform with reverse diastolic flow. The between-observer variations in the manual measurements ranged from 0.8% up to 9.4%. The overall variations associated with the automated traces were found to be smaller than or equal to those of the manual traces.
在体外对一种自适应实时多普勒峰值频率追踪算法进行了评估，并与手动峰值频率追踪结果进行了比较。使用计算机控制的泵在模拟血管系统的模型中生成生理血流波形。在ATL HDI上获取频谱波形以及诊断参数的实时估计值，包括最大收缩期、最小舒张期、时间平均峰值频率以及搏动性和阻力指数。研究了信噪比对测量参数的影响。发现测量参数的不精确性在一定程度上取决于波形形状；例如，对于正常肾波形，PI的不精确性为4.1%，对于具有舒张期反向血流的波形，PI的不精确性为8.5%。由九名操作人员手动追踪相同波形数据的峰值频率包络，并将所得诊断参数与从相同波形数据的自动峰值频率追踪中获得的参数进行比较。发现自动程序测量的参数与手动测量的参数之间的一致性在一定程度上取决于波形形状；例如，对于缺乏舒张期血流的肾波形，PI的偏差为1.3%，对于具有舒张期反向血流的波形，PI的偏差为12%。手动测量中观察者之间的变化范围为0.8%至9.4%。发现与自动追踪相关的总体变化小于或等于手动追踪的变化。
