Ovchinnikov A A, Tsvettsikh V E, Berdichevskiĭ B A, Lykov V N, Suktanbaev V R, Murychev A V
Urol Nefrol (Mosk). 1996 Jul-Aug(4):7-9.
The author's investigations led them to the conclusion that clinical manifestation of chronic pyelonephritis is associated with destabilization of lipid bilayer of red cell membranes, renal tissue, activation of lipid peroxidation (LPO), rising lipid and LPO products excretion with the urine. 31 patients with chronic pyelonephritis received combined therapy comprising essential phospholipids. 25 control patients with the same disease were not given essentiale-forte. Finally, the latter had longer fever duration, more active inflammation. The former had also low urine excretion of oxalates and normal lipid composition of biological membranes.
作者的研究使他们得出结论，慢性肾盂肾炎的临床表现与红细胞膜、肾组织脂质双层的不稳定、脂质过氧化（LPO）的激活、尿液中脂质和LPO产物排泄增加有关。31例慢性肾盂肾炎患者接受了包含必需磷脂的联合治疗。25例患有相同疾病的对照患者未给予易善复。最后，后者发热持续时间更长，炎症更活跃。前者尿草酸盐排泄量也较低，生物膜脂质组成正常。
