Fedorova O E, Balaian M S, Mikhaĭlov M I, Pavlova I P, Slasten O A, Patiutko Iu I, Sagaĭdak I V, Usmanov R K
Vopr Virusol. 1996 May-Jun;41(3):104-7.
Increase in the number of seropositive subjects in the population of European and North-American regions not endemic for hepatitis E stimulated research in this field. This study was aimed at investigating the incidence of IgG antibodies to hepatitis E virus (anti-HEV-IgG) in subjects with different liver diseases and in groups at increased risk of infection in a nonendemic region. In patients with different diseases of the liver the incidence of anti-HEV-IgG varied from 5.1 to 14.3%, in medical workers and former blood donors not allowed to donate blood because of increased transaminase levels in the blood 5.1 and 5.3%, respectively. In the reference group this level was appreciably lower-only 1.8%, this being rather close to the incidence of anti-HEV-IgG in the population of a nonendemic region (2.1%). There were no seropositive women in the group of healthy pregnant women in a non-endemic region, whereas in an endemic region (in Kyrghyzstan) 15% of pregnant women were seropositive for anti-HEV.
在并非戊型肝炎流行地区的欧洲和北美地区人群中，血清反应阳性者数量的增加推动了该领域的研究。本研究旨在调查非流行地区不同肝病患者及感染风险增加人群中戊型肝炎病毒IgG抗体（抗HEV-IgG）的发生率。在患有不同肝病的患者中，抗HEV-IgG的发生率在5.1%至14.3%之间，在医务人员以及因血液中转氨酶水平升高而不允许献血的 former blood donors中，该发生率分别为5.1%和5.3%。在参照组中，这一水平明显较低，仅为1.8%，这与非流行地区人群中抗HEV-IgG的发生率（2.1%）相当接近。在非流行地区的健康孕妇组中没有血清反应阳性的女性，而在流行地区（吉尔吉斯斯坦），15%的孕妇抗HEV呈血清反应阳性。
