Fragnito C, Beghi C, Cavozza C, Saccani S, Contini S A, Barboso G
Cattedra di Chirurgia del Cuore e dei Grossi Vasi, Università degli Studi di Parma.
Acta Biomed Ateneo Parmense. 1995;66(5):195-201.
To determine if autotransfusion of unwashed shed mediastinal blood led to a reduction in the postoperative banked blood requirements were analyzed in a prospective study 82 patients undergoing myocardial revascularization during 1994 at Cardiovascular Surgery Center of Parma, randomized to receive (ATS) or not (noATS) the system. No differences were noted between two groups in terms of clinical parameters; likewise the operative characteristics were similar for the two groups. The mean 24-hours postoperative blood loss was 719.5 +/- 196 ml in the ATS group and 843 +/- 292 ml in the nonATS group (p = 0.027); the mean volume autotransfused in the ATS group was 416 +/- 167 ml. There were no reoperations for bleeding. In the nonATS group 65.8% of patients required postoperative homologous transfusions compared with 41.5% in the ATS group (p = 0.05). The mean immediate and 24-hour postoperative hemoglobin values were similar in the two groups, but at hospital discharge were 21.1 +/- 1.4 g/dL in the nonATS group and 11.3 +/- 1.4 g/dL in the ATS (p = 0.015). By logistic stepwise multiple analysis were identified as risk factors for banked blood requirement the variables: age, preoperative blood drawing patient, blood drawing before institution of cardiopulmonary bypass and postoperative blood loss. Non use of ATS was not a significant incremental risk factor for banked blood requirement, furthermore we think that use of ATS system is a primary blood volume support and confers to reduce homologous transfusions and their related complications after cardiac operations.
为了确定未洗涤的纵隔引流血自体输血是否能减少术后库存血需求量,我们对帕尔马心血管外科中心1994年接受心肌血运重建术的82例患者进行了一项前瞻性研究,这些患者被随机分为接受(ATS)或不接受(noATS)该系统的两组。两组在临床参数方面没有差异;同样,两组的手术特征相似。ATS组术后24小时平均失血量为719.5±196ml,非ATS组为843±292ml(p = 0.027);ATS组平均自体输血量为416±167ml。没有因出血而进行再次手术的情况。非ATS组65.8%的患者术后需要输注同源血,而ATS组为41.5%(p = 0.05)。两组术后即刻和24小时的血红蛋白平均值相似,但出院时非ATS组为21.1±1.4g/dL,ATS组为11.3±1.4g/dL(p = 0.015)。通过逻辑逐步多元分析确定库存血需求的危险因素为以下变量:年龄、术前患者抽血、体外循环建立前抽血和术后失血量。未使用ATS不是库存血需求的显著增加危险因素,此外,我们认为使用ATS系统是主要的血容量支持措施,有助于减少心脏手术后同源输血及其相关并发症。