Suppr超能文献

经皮射频神经切断术治疗慢性颈椎关节突关节疼痛

Percutaneous radio-frequency neurotomy for chronic cervical zygapophyseal-joint pain.

作者信息

Lord S M, Barnsley L, Wallis B J, McDonald G J, Bogduk N

机构信息

Faculty of Medicine, University of Newcastle, Callaghan, NSW, Australia.

出版信息

N Engl J Med. 1996 Dec 5;335(23):1721-6. doi: 10.1056/NEJM199612053352302.

Abstract

BACKGROUND

Chronic pain in the cervical zygapohyseal joints is a common problem after whiplash injury, but treatment is difficult. Percutaneous radiofrequency neurotomy can relieve the pain by denaturing the nerves innervating the painful joint, but the efficacy of this treatment has not been established.

METHODS

In a randomized, double-blind trial, we compared percutaneous radio-frequency neurotomy in which multiple lesions were made and the temperature of the electrode making the lesions was raised to 80 degrees C with a control treatment using an identical procedure except that the radio-frequency current was not turned on. We studied 24 patients (9 men and 15 women; mean age, 43 years) who had pain in one or more cervical zygapophyseal joints after an automobile accident (median duration of pain, 34 months). The source of their pain had been identified with the use of double-blind, placebo-controlled local anesthesia. Twelve patients received each treatment. The patients were followed by telephone interviews and clinic visits until they reported that their pain had returned to 50 percent of the preoperative level.

RESULTS

The median time that elapsed before the pain returned to at least 50 percent of the preoperative level was 263 days in the active-treatment group and 8 days in the control group (P=0.04). At 27 weeks, seven patients in the active-treatment group and one patient in the control group were free of pain. Five patients in the active-treatment group had numbness in the territory of the treated nerves, but none considered it troubling.

CONCLUSIONS

In patients with chronic cervical zygapophyseal-joint pain confirmed with double-blind, placebo-controlled local anesthesia, percutaneous radio-frequency neurotomy with multiple lesions of target nerves can provide lasting relief.

摘要

背景

颈椎小关节慢性疼痛是挥鞭样损伤后常见的问题,但治疗困难。经皮射频神经切断术可通过使支配疼痛关节的神经变性来缓解疼痛,但该治疗方法的疗效尚未确定。

方法

在一项随机双盲试验中,我们比较了制造多个损伤且将制造损伤的电极温度升至80摄氏度的经皮射频神经切断术与采用相同操作但不开启射频电流的对照治疗。我们研究了24例患者(9例男性和15例女性;平均年龄43岁),这些患者在汽车事故后一个或多个颈椎小关节疼痛(疼痛中位持续时间34个月)。通过双盲、安慰剂对照局部麻醉确定了他们的疼痛来源。每组12例患者接受每种治疗。通过电话访谈和门诊随访患者,直到他们报告疼痛恢复到术前水平 的50%。

结果

积极治疗组疼痛恢复到至少术前水平50%之前的中位时间为263天,对照组为8天(P = 0.04)。在27周时,积极治疗组7例患者和对照组1例患者无疼痛。积极治疗组5例患者在治疗神经支配区域出现麻木,但无人认为这令人困扰。

结论

在经双盲、安慰剂对照局部麻醉确诊为慢性颈椎小关节疼痛的患者中,对靶神经进行多处损伤的经皮射频神经切断术可提供持久缓解。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验