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酿酒酵母的己糖转运蛋白家族。

The hexose transporter family of Saccharomyces cerevisiae.

作者信息

Kruckeberg A L

机构信息

Department of Biological Chemistry, UCLA School of Medicine, CHS 33-257, 10833 Le Conte Avenue, Los Angeles, CA 90095-1737, USA.

出版信息

Arch Microbiol. 1996 Nov;166(5):283-92. doi: 10.1007/s002030050385.

Abstract

Saccharomyces cerevisiae accomplishes high rates of hexose transport. The kinetics of hexose transport are complex. The capacity and kinetic complexity of hexose transport in yeast are reflected in the large number of sugar transporter genes in the genome. Twenty hexose transporter genes exist in S. cerevisiae. Some of these have been found by genetic means; many have been discovered by the comprehensive sequencing of the yeast genome. This review codifies the nomenclature of the hexose transporter genes and describes the sequence homology and structural similarity of the proteins they encode. Information about the expression and function of the transporters is presented. Access to the sequences of the genes and proteins at three sequence databases is provided via the World Wide Web.

摘要

酿酒酵母能实现较高的己糖转运速率。己糖转运的动力学较为复杂。酵母中己糖转运的能力和动力学复杂性体现在基因组中大量的糖转运蛋白基因上。酿酒酵母中存在20个己糖转运蛋白基因。其中一些是通过遗传学方法发现的;许多是通过酵母基因组的全面测序发现的。本综述整理了己糖转运蛋白基因的命名法,并描述了它们所编码蛋白质的序列同源性和结构相似性。还介绍了转运蛋白的表达和功能信息。可通过万维网访问三个序列数据库中的基因和蛋白质序列。

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