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The effect of electrophoretic lignocaine blockade in the region of the carotid sinuses on spontaneous and water diuresis.

作者信息

Kiersz J

出版信息

Int Urol Nephrol. 1977;9(1):53-65. doi: 10.1007/BF02082666.

DOI:10.1007/BF02082666
PMID:893026
Abstract

The effect of electrophoretic lignocaine blockade in the region of the carotid sinuses on changes in the intensity of spontaneous and water diuresis was investigated on anaesthetized dogs. After the blockade a reduction in spontaneous diuresis was observed and a marked and statistically significant restriction of water diuresis was noted as compared with the control experiments. The reduction in diuresis after the blockade was of a brief duration and did not appear to be related to changes in the intensity of the filtration through the kidneys, which was only slightly lower, but to changes in reabsorption. In all probability, the carotid blockade is connected with a dominance of hormonal effects by elimination of the effect of the nervi vagi, osmoreceptors of the carotid arteries and in particular the chemoreceptors of the carotid body.

摘要

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本文引用的文献

1
The effect of carotid occlusion upon the intrasinusal pressure with special reference to vascular communications between the carotid and vertebral circulations in the dog, cat and rabbit.颈动脉闭塞对窦内压力的影响，特别提及狗、猫和兔的颈动脉与椎动脉循环之间的血管交通。
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The excretion of administered sodium chloride by the conscious dog, and the effect of occlusion of the carotid arteries.
清醒犬对注入氯化钠的排泄以及颈动脉闭塞的影响。
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4
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Proc Soc Exp Biol Med. 1964 Jun;116:270-3. doi: 10.3181/00379727-116-29222.
5
The effect of vagotomy and denervation of the carotid sinus on diuresis following plasma volume expansion.迷走神经切断术和颈动脉窦去神经支配对血浆容量扩张后利尿的影响。
Can J Biochem Physiol. 1959 Jan;37(1):81-90.
6
The effect on urinary volume and composition of the ingestion of 0.9 per cent sodium chloride and of occlusion of the carotid arteries.摄入0.9%氯化钠以及颈动脉闭塞对尿量和成分的影响。
Q J Exp Physiol Cogn Med Sci. 1958 Oct;43(4):367-83. doi: 10.1113/expphysiol.1958.sp001350.
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Renal excretion of water and salt.水和盐的肾脏排泄。
Lancet. 1957 Dec 28;273(7009):1295-8. doi: 10.1016/s0140-6736(57)91635-5.
8
The renal clearance of alkali-stable inulin.碱稳定菊粉的肾脏清除率。
J Clin Invest. 1955 Oct;34(10):1520-3. doi: 10.1172/JCI103204.
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Role of the vagus in body water regulation.
Am J Physiol. 1970 May;218(5):1333-6. doi: 10.1152/ajplegacy.1970.218.5.1333.
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[Blockade of the carotid sinus by means of electrophoresis in the treatment of bronchial asthma].[通过电泳法阻断颈动脉窦治疗支气管哮喘]
Pol Tyg Lek. 1970 Apr 20;25(16):566-9.