Yawn B P, Yawn R A, Lydick E
Department of Research, Olmsted Medical Center, Rochester, Minnesota, USA.
Clin Ther. 1996 Sep-Oct;18(5):877-86; discussion 876. doi: 10.1016/s0149-2918(96)80048-8.
Otitis media is a common and costly condition of childhood, with a great potential for cost savings from an effective vaccine. We present a population-based survey of the family burden of otitis media and compare it with another common childhood illness, varicella, for which vaccine prevention is available and cost-effective. We report yearly rates of affected children, complications, medication use, hospitalizations, parental work absences, and use of special sick-child day care in a population of 4557 households containing 9047 children younger than 13 years of age. Of the 9047 children in the sample, 26.1% were affected by otitis media in the year of the study; 68% of children in the second year of life had at least one episode. About one third of families lost workdays due to otitis media in their children, with an overall average loss of about 3 hours per affected child. Compared with the community burden of varicella, otitis media involves a greater total burden in terms of the number of affected children, the number of episodes, physician visits, prescription drugs, hospitalizations, and surgical procedures. Work loss was 3.4 times greater per family with a varicella case, but the number of families affected by otitis media was 3.3 times greater than for varicella, so that the total amount of family work loss was about the same for both illnesses for the year. The community burden of otitis media should be studied in a population-based longitudinal manner that includes parental work loss as well as health care costs to accurately determine the potential cost-benefit of prevention programs.
中耳炎是儿童期常见且代价高昂的病症,有效的疫苗具有巨大的成本节约潜力。我们开展了一项基于人群的中耳炎家庭负担调查,并将其与另一种常见的儿童疾病水痘进行比较,水痘有可用且具成本效益的疫苗预防措施。我们报告了在包含9047名13岁以下儿童的4557户家庭人群中,受影响儿童的年发病率、并发症、药物使用情况、住院情况、家长误工情况以及特殊病童日托的使用情况。在该样本的9047名儿童中,26.1%在研究当年受到中耳炎影响;68%的儿童在出生后第二年至少有过一次发病。约三分之一的家庭因孩子患中耳炎而误工,每个患病儿童平均误工约3小时。与水痘的社区负担相比,就受影响儿童数量、发病次数、看医生次数、处方药使用、住院情况和外科手术而言,中耳炎的总体负担更大。水痘病例家庭的误工天数是前者的3.4倍,但受中耳炎影响的家庭数量是水痘的3.3倍,因此当年这两种疾病导致的家庭误工总量大致相同。应以基于人群的纵向方式研究中耳炎的社区负担,其中包括家长误工损失以及医疗保健成本,以准确确定预防项目的潜在成本效益。