Kirby M A, Steineke T C
Department of Physiology, Loma Linda University School of Medicine, CA 92350, USA.
Perspect Dev Neurobiol. 1996;3(3):177-94.
Much is known about the morphological development of mammalian retinal ganglion cells. However, relatively little is understood about the mechanisms that direct dendritic development and determine ganglion cell morphology, mosaic organization, and foveal development. In the following, we review current data on primate retinal ganglion cell development and integrate it with information from other species into a general model of dendritic development. Furthermore, we propose that this model not only explains ganglion cell dendritic development, but also accounts for the establishment of retinal ganglion cell mosaics and the timing of foveal formation.
关于哺乳动物视网膜神经节细胞的形态发育，我们已经了解很多。然而，对于指导树突发育并决定神经节细胞形态、镶嵌组织和中央凹发育的机制，我们了解得相对较少。在接下来的内容中，我们将回顾关于灵长类视网膜神经节细胞发育的现有数据，并将其与来自其他物种的信息整合到一个树突发育的通用模型中。此外，我们提出这个模型不仅可以解释神经节细胞树突的发育，还可以解释视网膜神经节细胞镶嵌的建立以及中央凹形成的时间。
