Tamura S, Hirao M, Shiozaki H, Inoue M, Hashimoto T, Hori S, Ohkata I, Asano H, Monden M
Department of Surgery II, Osaka University Medical School, Japan.
Surg Today. 1996;26(11):945-8. doi: 10.1007/BF00311803.
A newly designed coil esophageal endoprosthesis was developed using a thermal shape-memory titanium-nickel alloy. The major advantages of this stent lie in (a) its small diameter while in its compressed state in ice water and (b) the large lumen which is achieved once it has been warmed to body temperature. The technical feasibility and tissue compatibility of this stent were tested on four beagle dogs: two with an anastomotic stricture and two with a stenosis induced by the injection of monoethanolamine oleate. The teflon-coated stent was inserted under fluoroscopy and removed 4 weeks after implantation. No signs of esophageal reobstruction were observed in any of the animals after implantation or extraction of the stent, although the dog which had received the first stent without teflon coating developed obstruction caused by granulation tissue. Our preliminary experience strongly suggests that the shape-memory alloy stent with teflon coating may be used in the endoscopic treatment of anastomotic stenosis after esophagectomy, as well as of esophageal obstruction caused by carcinoma.
一种新设计的螺旋形食管内支架采用热形状记忆钛镍合金制成。这种支架的主要优点在于：（a）在冰水中处于压缩状态时直径较小；（b）升温至体温后能形成较大的管腔。在四只比格犬身上测试了这种支架的技术可行性和组织相容性：两只患有吻合口狭窄，两只因注射油酸单乙醇胺导致狭窄。在荧光透视引导下插入涂有特氟龙的支架，并在植入4周后取出。植入或取出支架后，在任何动物身上均未观察到食管再梗阻的迹象，不过，第一只接受未涂特氟龙支架的犬出现了由肉芽组织引起的梗阻。我们的初步经验有力地表明，涂有特氟龙的形状记忆合金支架可用于内镜治疗食管切除术后的吻合口狭窄以及癌性食管梗阻。
