Bezzi M, Orsi F, Salvatori F M, Maccioni F, Rossi P
Department of Radiology, University of Rome La Sapienza, Italy.
J Vasc Interv Radiol. 1994 Mar-Apr;5(2):287-93. doi: 10.1016/s1051-0443(94)71485-8.
Technical characteristics and clinical efficacy of a new metallic stent for the management of biliary obstruction were investigated in a clinical study.
From February 1991 to January 1993, 35 self-expandable, nickel-titanium alloy wire-mesh stents (diameter, 10 mm; length, 6 cm) were placed in 19 patients with obstructive jaundice due to cholangiocarcinoma (n = 6), pancreatic carcinoma (n = 5), lymph node metastasis to the liver hilum (n = 5), gallbladder carcinoma (n = 2), and intraductal papillary mucosal hyperplasia (n = 1).
Stent placement was successful in 18 of 19 patients. In one patient, stent dislodgement occurred after correct release; no other procedure-related complications or deaths occurred within 30 days following the procedure. Two (11%) of the remaining 18 patients are alive at 11 months; 16 (89%) died after a mean survival of 7.4 months. Two of three patients with stent obstruction underwent repeated intervention. Adequate palliation from jaundice was achieved without further intervention in 83% of cases. The mean stent patency was not less than 7 months.
Use of these metallic stents reestablished bile flow in the occluded biliary tree. Their efficacy and patency rate were also adequate.
在一项临床研究中调查一种用于处理胆道梗阻的新型金属支架的技术特性和临床疗效。
从1991年2月至1993年1月，将35个自膨式镍钛合金丝网支架（直径10毫米；长度6厘米）放置于19例因胆管癌（n = 6）、胰腺癌（n = 5）、肝门淋巴结转移（n = 5）、胆囊癌（n = 2）及导管内乳头状黏膜增生（n = 1）导致梗阻性黄疸的患者体内。
19例患者中有18例支架置入成功。1例患者在正确释放后支架发生移位；术后30天内未发生其他与手术相关的并发症或死亡。其余18例患者中有2例（11%）在11个月时存活；16例（89%）在平均存活7.4个月后死亡。3例支架阻塞患者中有2例接受了再次干预。83%的病例在未进一步干预的情况下实现了黄疸的充分缓解。支架平均通畅时间不少于7个月。
使用这些金属支架可使闭塞的胆道系统重新建立胆汁流动。其疗效和通畅率也较为理想。
