Grossman R, Yehuda R, Boisoneau D, Schmeidler J, Giller E L
Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA.
Biol Psychiatry. 1996 Dec 1;40(11):1100-5. doi: 10.1016/S0006-3223(95)00600-1.
The prolactin and cortisol responses to dexamethasone (0.5 mg) were studied in combat veterans with (n = 18) and without (n = 12) posttraumatic stress disorder (PTSD) and normal controls (n = 18). Both veteran groups demonstrated greater prolactin suppression than the normals. In contrast, only veterans with PTSD showed an enhanced cortisol suppression in response to dexamethasone. These findings suggest that the prolactin response to dexamethasone may reflect a feature of combat exposure rather than PTSD per se.
研究了患有创伤后应激障碍（PTSD）的（n = 18）和未患创伤后应激障碍的（n = 12）退伍军人以及正常对照组（n = 18）对（0.5毫克）地塞米松的催乳素和皮质醇反应。两个退伍军人组的催乳素抑制程度均高于正常人。相比之下，只有患有PTSD的退伍军人对地塞米松的反应表现出增强的皮质醇抑制。这些发现表明，催乳素对地塞米松的反应可能反映了战斗暴露的一个特征，而非PTSD本身。
