Haworth J
Nurs Stand. 1996 Sep 25;11(1):31-4. doi: 10.7748/ns1996.09.11.1.31.c2427.
This study assessed the difference in efficacy and patient morbidity when asthma drug therapy was administered by either a dry powder device (DPD) or metered dose inhaler (MDI). It assessed 27 patients who had used an MDI for at least six months before transferring to a DPD because of inadequate inhaler technique. Documentary evidence was collected retrospectively from the medical records six months before and six months after the change and outcomes were measured by daily bronchodilator therapy, daily inhaled steroid therapy, frequency of night-time wakening due to asthma symptoms, and peak expiratory flow rates. Patient symptoms and asthma control were found to be improved by the correct delivery of medication via DPD compared with an MDI.
本研究评估了使用干粉吸入装置(DPD)或定量吸入器(MDI)进行哮喘药物治疗时疗效和患者发病率的差异。研究评估了27名患者,这些患者因吸入技术不足在使用MDI至少六个月后转用DPD。回顾性收集了转换前六个月和转换后六个月的病历中的书面证据,并通过每日支气管扩张剂治疗、每日吸入性类固醇治疗、因哮喘症状夜间醒来的频率以及呼气峰值流速来衡量结果。结果发现,与MDI相比,通过DPD正确给药可改善患者症状和哮喘控制情况。