Bloechle M, Bollmann R, Wit J, Buttenberg S, Kursawe R, Guski H
Department of Prenatal Diagnosis and Therapy, University Hospital Charite, Berlin, Germany.
Ultrasound Obstet Gynecol. 1996 Jan;7(1):64-7. doi: 10.1046/j.1469-0705.1996.07010064.x.
In spite of the fact that most anomalies can be accurately diagnosed prenatally, one may be confronted with an extremely rare fetal abnormality that has never been described before. We report a case of a neuroectodermal cyst arising from the posterior neuropore. After 21 weeks of gestation a fetal anechoic intra- and extra-abdominal tumor was detected. The mass grew to 75 x 41 x 33 mm at 35 weeks. Initially it was believed to be a sacrococcygeal teratoma. Serial scans and Doppler ultrasound examinations were performed, which demonstrated fetal well-being. Color Doppler imaging failed to demonstrate increased tumoral perfusion. After elective Cesarean section, the tumor was excised. The postoperative course was complicated by recurrent infections of the urinary tract due to neurological damage to the bladder. There was also impaired function of the anal sphincter. The histological finding of a monolayer of neuroepithelial cells and melanocytes led to the diagnosis of a neuroectodermal cyst.
尽管大多数异常情况可在产前得到准确诊断，但仍可能会遇到一种极为罕见、此前从未有过描述的胎儿异常情况。我们报告一例源自后神经孔的神经外胚层囊肿病例。妊娠21周时检测到胎儿腹内和腹外有一无回声肿瘤。孕35周时该肿块增大至75×41×33毫米。最初认为它是骶尾部畸胎瘤。进行了系列扫描和多普勒超声检查，结果显示胎儿状况良好。彩色多普勒成像未显示肿瘤灌注增加。择期剖宫产术后，切除了肿瘤。术后病程因膀胱神经损伤导致反复尿路感染而复杂化。肛门括约肌功能也受损。单层神经上皮细胞和黑素细胞的组织学发现确诊为神经外胚层囊肿。
