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儿童HIV的脑血管并发症

Cerebrovascular complications of HIV in children.

作者信息

Shah S S, Zimmerman R A, Rorke L B, Vezina L G

机构信息

Department of Radiology, Children's Hospital of Philadelphia, PA 19104, USA.

出版信息

AJNR Am J Neuroradiol. 1996 Nov-Dec;17(10):1913-7.

Abstract

Two uncommon but important cerebrovascular manifestations of human immunodeficiency virus (HIV) infection in children are arteritis with formation of fusiform aneurysms and arterial sclerosis with vascular occlusion. We studied the CT and MR imaging features of HIV in two girls and one boy (9 to 18 years old) and compared them with autopsy findings in two patients. One of the children had findings consistent with small areas of subacute infarction and the other two had fusiform dilatation of the major vessels of the circle of Willis. The ischemic lesions and arteriopathy were confirmed at autopsy. In one patient, an incidental B-cell lymphoma (not visible on the imaging studies) was diagnosed.

摘要

人类免疫缺陷病毒(HIV)感染在儿童中导致的两种罕见但重要的脑血管表现为伴有梭形动脉瘤形成的动脉炎和伴有血管闭塞的动脉硬化。我们研究了两名女孩和一名男孩(9至18岁)HIV感染的CT和MR成像特征,并将其与两名患者的尸检结果进行了比较。其中一名儿童的表现符合小面积亚急性梗死,另外两名儿童则出现了Willis环主要血管的梭形扩张。尸检证实了缺血性病变和动脉病。在一名患者中,诊断出了偶然发现的B细胞淋巴瘤(影像学检查未显示)。

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