Strauss D, Zigman W B
Department of Statistics, University of California, Riverside 92521, USA.
Am J Ment Retard. 1996 Nov;101(3):269-81.
Among adults with mental retardation, mortality rates for those with Down syndrome are higher than for those without Down syndrome. We studied age-related changes in functioning and their relation to subsequent mortality in adults with mental retardation. Among people without Down syndrome, recent loss of basic skills was associated with substantially elevated mortality rates. This was not so in the Down syndrome group, however. Adults with Down syndrome tended to experience regression in adaptive behavior earlier than did those without Down syndrome. Incidence rates in the two groups diverged subsequent to age 40. Adults without Down syndrome, however, did also tend to regress when older.
在患有智力障碍的成年人中，唐氏综合征患者的死亡率高于非唐氏综合征患者。我们研究了患有智力障碍的成年人功能随年龄的变化及其与随后死亡率的关系。在非唐氏综合征患者中，近期基本技能丧失与死亡率大幅上升有关。然而，唐氏综合征组并非如此。唐氏综合征成年人比非唐氏综合征成年人更早出现适应性行为退化。两组的发病率在40岁以后出现差异。不过，非唐氏综合征的成年人在年龄较大时也确实有退化的倾向。
