Graham S, Sim G, Laughren R, Chicoine J, Stephenson E, Leche G, McIntyre M, Murray D, Aoki F Y, Nicolle L E
Deer Lodge Centre, Winnipeg, Manitoba, Canada.
Infect Control Hosp Epidemiol. 1996 Nov;17(11):732-6. doi: 10.1086/647218.
To compare patient outcomes when percutaneous feeding tubes were changed routinely each month or only when necessary (prn).
Prospective, randomized, nonblinded crossover study of 6 months of routine monthly changes compared with 6 months of prn changes.
416-bed long-term-care facility.
26 permanent residents with nutrition managed through percutaneous gastrostomy or jejunostomy feeding tubes. The median age was 61.5 years; 8 (31%) also had tracheostomies, and 3 (12%) had indwelling urinary catheters.
The frequency of feeding tube changes was 40 per 1,000 patient-days during the 6 months of routine tube changes and 14 per 1,000 when tubes were changed prn (P < .001). There were no differences between the two study periods in frequency of stoma site infections, fever, episodes of emesis, and total antibiotic courses. The median duration in situ of feeding tubes with prn changes was 104 days. For both periods, feeding tubes were significantly more likely to fall out and require replacement with-in 24 hours of previous tube replacement.
There were no observed differences in clinical outcomes in long-term-care facility patients when feeding tubes were changed only as necessary as compared to routine monthly changes.
比较每月定期更换经皮饲管与仅在必要时(按需)更换时患者的结局。
前瞻性、随机、非盲交叉研究,对比6个月的每月定期更换与6个月的按需更换。
拥有416张床位的长期护理机构。
26名通过经皮胃造口术或空肠造口术饲管进行营养管理的长期居民。中位年龄为61.5岁;8名(31%)患者还进行了气管造口术,3名(12%)患者留置了导尿管。
在定期更换饲管的6个月期间,饲管更换频率为每1000患者日40次,按需更换时为每1000患者日14次(P < 0.001)。两个研究期间在造口部位感染频率、发热、呕吐发作次数和抗生素总疗程方面无差异。按需更换时饲管的中位在位持续时间为104天。在两个期间,饲管在先前饲管更换后24小时内更有可能脱出并需要更换。
与每月定期更换相比,在长期护理机构患者中仅在必要时更换饲管,未观察到临床结局存在差异。