Kim K H, Yoon T J, Oh C W, Ko G H, Kim T H
Department of Dermatology and Anatomical Pathology, College of Medicine, Chinju, Korea.
J Korean Med Sci. 1996 Oct;11(5):454-6. doi: 10.3346/jkms.1996.11.5.454.
The association of exposure to bleomycin with the development of scleroderma-like cutaneous abnormalities has been reported. We experienced a case of scleroderma involving the hands, feet, and forearms after bleomycin chemotherapy. The present report supports the possible causal relation of bleomycin with scleroderma. Regarding the widespread use of bleomycin, this complication is thought to be under appreciated.
已报道接触博来霉素与硬皮病样皮肤异常的发生有关。我们遇到一例在博来霉素化疗后出现累及手部、足部和前臂的硬皮病病例。本报告支持博来霉素与硬皮病之间可能存在因果关系。鉴于博来霉素的广泛使用,这种并发症可能未得到充分认识。