Roelofse J A, van der Bijl P
Division of Maxillo-facial Anesthesia, University of Stellenbosch, Tygerberg, South Africa.
Anesth Prog. 1994;41(3):81-2.
A 21-yr-old mentally retarded and cardiovascularly compromised woman who required dental restorative work and extractions was admitted to our clinic. We had previously successfully sedated her with propofol and midazolam. In this case she was sedated with a 1% propofol solution administered initially at a rate of 8 mg/kg-hr. After 5 min, the infusion rate was lowered to 5 mg/kg-hr, and after the local anesthetic injection, was adjusted to 3 mg/kg-hr. After 15 min, the patient became restless, and the propofol infusion rate was again increased to 5 mg/kg-hr. The patient's airway was well maintained during the entire procedure; she remained well sedated, and no adverse effects were experienced.
一名21岁智力发育迟缓且有心血管问题的女性因需要进行牙齿修复和拔牙而入住我们的诊所。我们之前曾用丙泊酚和咪达唑仑成功为她实施过镇静。此次，我们用1%的丙泊酚溶液对她进行镇静，初始输注速度为8毫克/千克·小时。5分钟后，输注速度降至5毫克/千克·小时，在注射局部麻醉剂后，又调整至3毫克/千克·小时。15分钟后，患者变得烦躁不安，丙泊酚输注速度再次增至5毫克/千克·小时。在整个操作过程中，患者气道维持良好；她一直处于深度镇静状态，且未出现不良反应。
