Hata R I
Department of Tissue Physiology, Tokyo Medical and Dental University, Japan.
Cell Biol Int. 1996 Jan;20(1):59-65. doi: 10.1006/cbir.1996.0009.
Morphogenesis is an old, and one of the latest, fascinating fields in biological science and a huge number of papers on molecular mechanisms underlying it have been published. But most of the works and reviews on these mechanisms pertain to molecules of, as it were, the planning or design of morphogenesis, such as morphogens and homeodomain proteins. In this review, I will describe the function of extracellular matrix (ECM) and other cell adhesion molecules in morphogenesis as that of actual morpho-creating molecules, morphocreators, and discuss their roles as positional information-pertaining molecules.
形态发生是生物科学中一个古老且最新颖迷人的领域之一，关于其潜在分子机制的大量论文已发表。但关于这些机制的大多数研究和综述都涉及到可以说是形态发生的规划或设计分子，比如形态发生素和同源结构域蛋白。在这篇综述中，我将描述细胞外基质（ECM）和其他细胞黏附分子在形态发生中的功能，将其视为实际的形态塑造分子，即形态塑造者，并讨论它们作为与位置信息相关分子的作用。
