Summerbell D, Smith J C, Maden M
Limb Development Group, National Institute for Medical Research, Mill Hill, London.
In Vivo. 1991 Sep-Oct;5(5):457-71.
Embryologists have dreamed of their own particular philosophers stone for 100 years. During that time they have repeatedly demonstrated the likely existence of signalling molecules or morphogens that control the pattern of development in the embryo. Now at last seems possible that some of these morphogens may have been identified. We review current evidence for the molecular basis of positional information.
100年来,胚胎学家们一直梦想着能找到他们自己独特的点金石。在此期间,他们反复证明了可能存在控制胚胎发育模式的信号分子或形态发生素。现在,终于有可能已经鉴定出其中一些形态发生素了。我们回顾了关于位置信息分子基础的现有证据。