Cristina S, Sandrini G, Ruiz L, Verri A P, Musicco M, Nappi G
Neuroepidemiological Laboratory, Casimiro Mondino Neurological Institute, Pavia, Italy.
Funct Neurol. 1996 Jan-Feb;11(1):53-8.
Neuronal Hyperexcitability Syndrome (NHS) is a nosographic picture which is difficult to diagnose, due to the lack of specific standard diagnostic criteria. With slightly varying symptoms the syndrome has also been defined as Spasmophilia and Hyperventilation Syndrome. It is difficult to distinguish between NHS and panic attack disorder as there is considerable overlapping of symptomatology. We aimed to propose a standardized card which will be the first step toward a valid diagnosis of this complex neuropsychiatric problem. This card, which will be validated and of which the reliability will be evaluated, is proposed for clinical and research purposes. The card is made up of 6 parts (113 items) covering: personal data, pharmacological treatment, persistent diseases and related therapies, symptomatology trend, factors interfering with calcium-magnesium homeostasis and symptom assessment. The symptom assessment section is essential for the checking of diagnostic criteria and the earlier sections are important for the monitoring of other factors which can cause symptoms able to simulate NHS. There are also two special sections for recording laboratory tests and patients' psychic profiles.
神经元兴奋性亢进综合征（NHS）是一种难以诊断的疾病分类情况，因为缺乏具体的标准诊断标准。由于症状略有不同，该综合征也被定义为痉挛素质和换气过度综合征。由于症状学有相当大的重叠，所以很难区分NHS和惊恐障碍。我们旨在提出一张标准化卡片，这将是朝着有效诊断这一复杂神经精神问题迈出的第一步。这张卡片将进行验证并评估其可靠性，现出于临床和研究目的而提出。该卡片由6部分（113项）组成，涵盖：个人数据、药物治疗、慢性病及相关疗法、症状学趋势、干扰钙镁稳态的因素以及症状评估。症状评估部分对于检查诊断标准至关重要，而前面的部分对于监测其他可能导致类似NHS症状的因素很重要。还有两个特殊部分用于记录实验室检查和患者的心理状况。
