Mudzamiri W S, Peterson D E, Marufu T, Biellik R J, L'Herminez M
Zimbabwe Republic Police Medical Services, Police General Headquarters, Causeway, Zimbabwe.
Cent Afr J Med. 1996 Jul;42(7):195-7.
To carry out a survey in Masvingo District to determine the efficacy of measles vaccine.
A retrospective study, using existing health care facility records and interviews with care givers.
Using the standard WHO-EPI cluster sampling methodology, 30 clusters were randomly selected in Masvingo District.
14 or more children in each of the 30 clusters were selected.
Occurrence of measles or lack of it among the children aged 12 to 23 months, age at vaccination, status, the age at which the child had measles and availability of a health card.
In Masvingo District from 1987 to 1994, measles incidence remained very high, though mortality drastically declined. Using field survey data measles vaccine efficacy was estimated at 78.3pc (95pc CI 54.1; 89.8). Vaccine coverage was estimated to be 75pc.
The efficacy results fall at the lower end, but within the normal limits, of those expected for measles vaccine as used in Zimbabwe. Steps to increase vaccine coverage are of the highest priority.
在马斯温戈区开展一项调查，以确定麻疹疫苗的效力。
一项回顾性研究，利用现有的医疗保健机构记录并与照顾者进行访谈。
采用世卫组织扩大免疫规划标准整群抽样方法，在马斯温戈区随机选取30个群组。
在30个群组中，每个群组选取14名或更多儿童。
12至23个月龄儿童中麻疹的发生情况或未发生情况、接种疫苗的年龄、状况、儿童患麻疹的年龄以及健康卡的持有情况。
1987年至1994年期间，马斯温戈区的麻疹发病率仍然很高，不过死亡率大幅下降。根据现场调查数据，麻疹疫苗效力估计为78.3%（95%置信区间54.1；89.8）。疫苗接种覆盖率估计为75%。
效力结果处于津巴布韦使用的麻疹疫苗预期效力范围的下限，但在正常范围内。提高疫苗接种覆盖率的措施最为优先。
