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鼻内硫酸锌治疗对大鼠嗅觉辨别能力的评估。

Evaluation of intranasal zinc sulfate treatment on olfactory discrimination in rats.

作者信息

Slotnick B M, Gutman L A

出版信息

J Comp Physiol Psychol. 1977 Aug;91(4):942-50. doi: 10.1037/h0077370.

DOI:10.1037/h0077370
PMID:893754
Abstract

The effects of intranasal syringing with 5% zinc sulfate were assessed in rats trained in a wind-tunnel olfactometer to detect the presence of an odor or to discriminate odors of graded intensities. The syringing produced a severe but brief interference in olfactory performance. Full recovery of detection performance occurred within 72 hr after treatment. Initial recovery of odor intensity discrimination occurred in 2-8 days and full recovery within 8-10 days. These results suggest that intranasal syringing with ZnSO4 is not an adequate control for the effects of anosmia produced by olfactory bulbectomy.

摘要

在经过风洞嗅觉计训练以检测气味存在或辨别不同强度等级气味的大鼠中,评估了用5%硫酸锌进行鼻腔注射的效果。注射对嗅觉表现产生了严重但短暂的干扰。治疗后72小时内检测性能完全恢复。气味强度辨别最初在2 - 8天内恢复,8 - 10天内完全恢复。这些结果表明,用硫酸锌进行鼻腔注射不能充分控制嗅球切除所致嗅觉丧失的影响。

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