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信号识别颗粒及相关的小细胞质核糖核蛋白颗粒

The signal recognition particle and related small cytoplasmic ribonucleoprotein particles.

作者信息

Bovia F, Strub K

机构信息

Département de Biologie Cellulaire, Université de Genève, Switzerland.

出版信息

J Cell Sci. 1996 Nov;109 ( Pt 11):2601-8. doi: 10.1242/jcs.109.11.2601.

DOI:10.1242/jcs.109.11.2601
PMID:8937977
Abstract

Recently, a number of novel small cytoplasmic ribonucleoprotein particles have been identified that comprise RNA and protein subunits related to the signal recognition particle (SRP). Here we discuss the latest results on the structure and functions of SRP together with the structures and putative functions of the novel SRP-related ribonucleoprotein particles.

摘要

最近,人们发现了一些新型的小细胞质核糖核蛋白颗粒,它们由与信号识别颗粒(SRP)相关的RNA和蛋白质亚基组成。在此,我们将讨论SRP的结构和功能的最新研究成果,以及新型SRP相关核糖核蛋白颗粒的结构和假定功能。

相似文献

1
The signal recognition particle and related small cytoplasmic ribonucleoprotein particles.信号识别颗粒及相关的小细胞质核糖核蛋白颗粒
J Cell Sci. 1996 Nov;109 ( Pt 11):2601-8. doi: 10.1242/jcs.109.11.2601.
2
Requirement of GTP hydrolysis for dissociation of the signal recognition particle from its receptor.信号识别颗粒从其受体解离对GTP水解的需求。
Science. 1991 May 24;252(5009):1171-3. doi: 10.1126/science.252.5009.1171.
3
The SRP9/14 subunit of the signal recognition particle (SRP) is present in more than 20-fold excess over SRP in primate cells and exists primarily free but also in complex with small cytoplasmic Alu RNAs.信号识别颗粒(SRP)的SRP9/14亚基在灵长类细胞中的含量比SRP高出20多倍,主要以游离形式存在,但也与小细胞质Alu RNA形成复合物。
Mol Biol Cell. 1995 Apr;6(4):471-84. doi: 10.1091/mbc.6.4.471.
4
In vivo assembly of eukaryotic signal recognition particle: A still enigmatic process involving the SMN complex.真核信号识别颗粒的体内组装:一个涉及 SMN 复合物的仍然神秘的过程。
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5
Removal of the Alu structural domain from signal recognition particle leaves its protein translocation activity intact.从信号识别颗粒中去除Alu结构域后,其蛋白质转运活性保持完整。
Nature. 1986;320(6057):81-4. doi: 10.1038/320081a0.
6
GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation.蛋白质转运起始过程中信号识别颗粒的GTP结合与水解
Nature. 1993 Nov 25;366(6453):351-4. doi: 10.1038/366351a0.
7
Nuclear export of signal recognition particle RNA is a facilitated process that involves the Alu sequence domain.信号识别颗粒RNA的核输出是一个涉及Alu序列结构域的易化过程。
J Cell Sci. 1994 Apr;107 ( Pt 4):903-12. doi: 10.1242/jcs.107.4.903.
8
Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor.4.5S RNA在细菌信号识别颗粒与其受体组装过程中的作用。
Science. 2000 Jun 2;288(5471):1640-3. doi: 10.1126/science.288.5471.1640.
9
Interaction of E. coli Ffh/4.5S ribonucleoprotein and FtsY mimics that of mammalian signal recognition particle and its receptor.大肠杆菌Ffh/4.5S核糖核蛋白与FtsY的相互作用模拟了哺乳动物信号识别颗粒及其受体的相互作用。
Nature. 1994 Feb 17;367(6464):657-9. doi: 10.1038/367657a0.
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RNA gymnastics in mammalian signal recognition particle assembly.哺乳动物信号识别颗粒组装中的RNA“体操”
RNA Biol. 2014;11(11):1330-4. doi: 10.1080/15476286.2014.996457.

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Direct binding of the Alu binding protein dimer SRP9/14 to 40S ribosomal subunits promotes stress granule formation and is regulated by Alu RNA.Alu结合蛋白二聚体SRP9/14与40S核糖体亚基的直接结合促进应激颗粒的形成,并受Alu RNA调控。
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Retrovirology. 2008 Jul 2;5:54. doi: 10.1186/1742-4690-5-54.
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Alu RNP and Alu RNA regulate translation initiation in vitro.Alu核糖核蛋白(Alu RNP)和Alu核糖核酸(Alu RNA)在体外调节翻译起始。
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Getting on target: the archaeal signal recognition particle.瞄准目标:古细菌信号识别颗粒
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