• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Thalidomide as an anti-TNF-alpha inhibitor: implications for clinical use.

作者信息

Klausner J D, Freedman V H, Kaplan G

机构信息

Laboratory of Cellular Physiology and Immunology, Rockefeller University, New York 10021-6399, USA.

出版信息

Clin Immunol Immunopathol. 1996 Dec;81(3):219-23. doi: 10.1006/clin.1996.0181.

DOI:10.1006/clin.1996.0181
PMID:8938097
Abstract
摘要

相似文献

1
Thalidomide as an anti-TNF-alpha inhibitor: implications for clinical use.
Clin Immunol Immunopathol. 1996 Dec;81(3):219-23. doi: 10.1006/clin.1996.0181.
2
Thalidomide and derivatives: immunological investigations of tumour necrosis factor-alpha (TNF-alpha) inhibition suggest drugs capable of selective gene regulation.沙利度胺及其衍生物:肿瘤坏死因子-α(TNF-α)抑制作用的免疫学研究表明,这些药物具有选择性基因调控能力。
Clin Exp Immunol. 1997 Nov;110(2):151-4. doi: 10.1111/j.1365-2249.1997.tb08310.x.
3
Therapeutic and prophylactic thalidomide in TNBS-induced colitis: synergistic effects on TNF-alpha, IL-12 and VEGF production.沙利度胺在三硝基苯磺酸诱导的结肠炎中的治疗和预防作用:对肿瘤坏死因子-α、白细胞介素-12和血管内皮生长因子产生的协同效应
World J Gastroenterol. 2007 Apr 21;13(15):2166-73. doi: 10.3748/wjg.v13.i15.2166.
4
Thalidomide suppresses NF-kappa B activation induced by TNF and H2O2, but not that activated by ceramide, lipopolysaccharides, or phorbol ester.沙利度胺可抑制由肿瘤坏死因子(TNF)和过氧化氢(H2O2)诱导的核因子κB(NF-κB)激活,但不能抑制由神经酰胺、脂多糖或佛波酯激活的NF-κB。
J Immunol. 2002 Mar 15;168(6):2644-51. doi: 10.4049/jimmunol.168.6.2644.
5
Thalidomide in rat liver cirrhosis: blockade of tumor necrosis factor-alpha via inhibition of degradation of an inhibitor of nuclear factor-kappaB.沙利度胺在大鼠肝硬化中的作用:通过抑制核因子κB抑制剂的降解来阻断肿瘤坏死因子-α
Pathobiology. 2006;73(2):82-92. doi: 10.1159/000094492.
6
Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression.沙利度胺通过下调髓样分化因子88(MyD88)的表达来抑制脂多糖诱导的肿瘤坏死因子-α的产生。
Innate Immun. 2009 Feb;15(1):33-41. doi: 10.1177/1753425908099317.
7
Exposure to the anti-TNF-alpha drug thalidomide induces apoptotic cell death in human T leukemic cells.接触抗TNF-α药物沙利度胺会诱导人T白血病细胞发生凋亡性细胞死亡。
Cell Mol Biol (Noisy-le-grand). 2003 Nov;49(7):1117-24.
8
Thalidomide analogs from diamines: Synthesis and evaluation as inhibitors of TNF-alpha production.基于二胺的沙利度胺类似物:合成及其作为肿瘤坏死因子-α产生抑制剂的评价
Chem Pharm Bull (Tokyo). 2007 Feb;55(2):223-6. doi: 10.1248/cpb.55.223.
9
Thalidomide: focus on its employment in rheumatologic diseases.沙利度胺:关注其在风湿性疾病中的应用。
Clin Exp Rheumatol. 2002 Sep-Oct;20(5):709-18.
10
Novel biological response modifiers derived from thalidomide.源自沙利度胺的新型生物反应调节剂。
Curr Med Chem. 1998 Jun;5(3):163-78.

引用本文的文献

1
Drug-induced Stevens Johnson syndrome and toxic epidermal necrolysis: Interpreting the systematic reviews on immunomodulatory therapies.药物性史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症:解读关于免疫调节疗法的系统评价
Asia Pac Allergy. 2023 Jun;13(2):72-76. doi: 10.5415/apallergy.0000000000000101. Epub 2023 Jun 6.
2
Targeting TNFα-mediated cytotoxicity using thalidomide after experimental cardiac arrest in rats: An exploratory study.在大鼠实验性心脏骤停后使用沙利度胺靶向肿瘤坏死因子α介导的细胞毒性:一项探索性研究。
Exp Ther Med. 2022 Jun;23(6):380. doi: 10.3892/etm.2022.11307. Epub 2022 Apr 8.
3
Systemic interventions for treatment of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome.
全身性治疗史蒂文斯-约翰逊综合征(SJS)、中毒性表皮坏死松解症(TEN)和 SJS/TEN 重叠综合征。
Cochrane Database Syst Rev. 2022 Mar 11;3(3):CD013130. doi: 10.1002/14651858.CD013130.pub2.
4
Current Perspectives on Severe Drug Eruption.当前对严重药物疹的看法。
Clin Rev Allergy Immunol. 2021 Dec;61(3):282-298. doi: 10.1007/s12016-021-08859-0. Epub 2021 Jul 17.
5
Repurposing of thalidomide and its derivatives for the treatment of SARS-coV-2 infections: Hints on molecular action.沙利度胺及其衍生物在治疗 SARS-CoV-2 感染中的再利用:分子作用的提示。
Br J Clin Pharmacol. 2021 Oct;87(10):3835-3850. doi: 10.1111/bcp.14792. Epub 2021 Mar 15.
6
Cytokine-Targeted Therapeutics for KSHV-Associated Disease.针对 KSHV 相关疾病的细胞因子靶向治疗。
Viruses. 2020 Sep 28;12(10):1097. doi: 10.3390/v12101097.
7
Thalidomide Promotes Morphine Efficacy and Prevents Morphine-Induced Tolerance in Rats with Diabetic Neuropathy.沙利度胺增强糖尿病性神经病变大鼠体内吗啡药效并预防吗啡诱导的耐受性。
Neurochem Res. 2016 Dec;41(12):3171-3180. doi: 10.1007/s11064-016-2041-7. Epub 2016 Aug 30.
8
In vivo screening and discovery of novel candidate thalidomide analogs in the zebrafish embryo and chicken embryo model systems.在斑马鱼胚胎和鸡胚胎模型系统中对新型沙利度胺类似物候选物进行体内筛选与发现。
Oncotarget. 2016 May 31;7(22):33237-45. doi: 10.18632/oncotarget.8909.
9
Etanercept exacerbates inflammation and pathology in a rabbit model of active pulmonary tuberculosis.依那西普会加剧活动性肺结核兔模型中的炎症和病理变化。
J Interferon Cytokine Res. 2014 Sep;34(9):716-26. doi: 10.1089/jir.2013.0123. Epub 2014 May 15.
10
Magnetic resonance imaging for monitoring the effects of thalidomide on experimental human breast cancers.磁共振成像用于监测沙利度胺对实验性人类乳腺癌的影响。
Eur Radiol. 2009 Jan;19(1):121-31. doi: 10.1007/s00330-008-1111-x. Epub 2008 Jul 30.