Thevadass K P, Pearson G J, Anstice H M, Davies E H
Department of Biomaterials, Eastman Dental Institute, London, UK.
Biomaterials. 1996 Feb;17(4):425-9. doi: 10.1016/0142-9612(96)89659-1.
The cariostatic action of the glass-ionomer cement has been attributed to its sustained release of fluoride. The fluoride in the set cement originates from the glass particles which are eroded, in part, during the setting reaction. In this study a water-activated glass-ionomer was mixed with sodium fluoride (NaF) solutions of different concentrations (0%, 2% and 4%). The different cements were used to prepare discs which were stored individually in demineralized water at 37 degrees C, the fluoride concentration of the storage solutions were measured, at intervals, until the specimens were 80 days old. The effect of the different mixing solutions on the working and setting times and compressive strength were also determined. It was found that the cement mixed with the 4% solution of NaF released significantly more fluoride than the water mixed control. The fluoride solution mixed materials had longer setting times than the control, but there was no significant difference in the compressive strengths. All the materials became progressively stronger on storage. Mixing the cement with a 4% solution of NaF increased the initial fluoride release of the glass-ionomer without seriously affecting other physical properties.
玻璃离子水门汀的防龋作用归因于其氟的持续释放。凝固后的水门汀中的氟源自玻璃颗粒，在凝固反应过程中，部分玻璃颗粒会被侵蚀。在本研究中，将一种水激活的玻璃离子水门汀与不同浓度（0%、2%和4%）的氟化钠（NaF）溶液混合。用不同的水门汀制备圆盘，将其分别储存在37℃的去离子水中，定期测量储存溶液中的氟浓度，直至样本达到80天龄。还测定了不同混合溶液对工作时间、凝固时间和抗压强度的影响。结果发现，与4%NaF溶液混合的水门汀释放的氟明显多于与水混合的对照物。与氟溶液混合的材料的凝固时间比对照物长，但抗压强度没有显著差异。所有材料在储存过程中都逐渐变强。将水门汀与4%的NaF溶液混合可增加玻璃离子水门汀的初始氟释放量，且不会严重影响其他物理性能。
