Gurian J H, Viñuela F, Guglielmi G, Gobin Y P, Duckwiler G R
Department of Radiological Sciences, University of California Los Angeles Medical Center, USA.
Neurosurgery. 1996 Dec;39(6):1150-4; discussion 1154-6. doi: 10.1097/00006123-199612000-00016.
Internal carotid artery aneurysms arising from the superior hypophyseal artery are frequently termed paraophthalmic or paraclinoid aneurysms, but they constitute a distinct anatomic entity. They are particularly amenable to endovascular treatment.
Between 1991 and 1995, we attempted treatment in 11 patients with superior hypophyseal artery aneurysms with Guglielmi detachable coil embolization and were successful in 10. Surgical exploration in seven of the patients was unsuccessful, three patients were considered to be at high risk for surgery or to have poor likelihood of surgical success by the referring neurosurgeon, and one patient refused operative clipping. Two aneurysms were giant (> 25 mm), three were large (10-25 mm), and six were small (< 10 mm). Of the six small aneurysms, two had wide necks (> 4 mm) and four had narrow necks (< or = 4 mm).
There were no technical or clinical complications related to embolization. Immediate complete aneurysm obliteration was obtained in five aneurysms, all of which were small. Four of the remaining five aneurysms had obliteration of the dome and body, leaving only a small remnant neck. The remaining semifusiform aneurysm represented our single treatment failure. Recanalization occurred in only one patient; that patient had a giant aneurysm. Nine of the 10 patients for whom embolization was successful had good or excellent clinical outcomes; there were no clinical deteriorations attributable to embolization.
We conclude that Guglielmi detachable coil embolization of superior hypophyseal artery aneurysms is an excellent treatment alternative, especially for smaller lesions.
起源于垂体上动脉的颈内动脉瘤常被称为眼旁或床突旁动脉瘤,但它们构成一个独特的解剖实体。它们尤其适合血管内治疗。
1991年至1995年间,我们尝试用 Guglielmi 可脱弹簧圈栓塞术治疗11例垂体上动脉动脉瘤患者,10例成功。7例患者的手术探查未成功,3例患者被转诊的神经外科医生认为手术风险高或手术成功可能性低,1例患者拒绝手术夹闭。2个动脉瘤为巨大型(>25mm),3个为大型(10 - 25mm),6个为小型(<10mm)。在6个小型动脉瘤中,2个有宽颈(>4mm),4个有窄颈(≤4mm)。
栓塞术未出现技术或临床并发症。5个小型动脉瘤立即完全闭塞。其余5个动脉瘤中有4个瘤顶和瘤体闭塞,仅留一小段残余颈。剩余的半梭形动脉瘤是我们唯一的治疗失败病例。仅1例患者出现再通,该患者为巨大动脉瘤。10例栓塞成功的患者中有9例临床结局良好或极好;无因栓塞导致的临床恶化情况。
我们得出结论,垂体上动脉动脉瘤的 Guglielmi 可脱弹簧圈栓塞术是一种极佳的治疗选择,尤其适用于较小病变。