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床突旁动脉瘤血管内可脱性弹簧圈栓塞术的临床及影像学结果:10年经验

Clinical and radiogical outcomes of endovascular detachable coil embolization in paraclinoid aneurysms : a 10-year experience.

作者信息

Jin Sung-Chul, Kwon Do Hoon, Ahn Jae-Sung, Kwun Byung-Duk, Song Young, Choi Choong-Gon

机构信息

Department of Neurological Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

出版信息

J Korean Neurosurg Soc. 2009 Jan;45(1):5-10. doi: 10.3340/jkns.2009.45.1.5. Epub 2009 Jan 31.

Abstract

OBJECTIVE

Direct surgical clipping of paraclinoid aneurysms poses technical challenges to even very experienced neurosurgeons, making endovascular treatment an alternative treatment modality in many centers. We have therefore retrospectively evaluated the safety and efficacy of endovascular detachable coil embolization of paraclinoid aneurysms.

METHODS

From June 1997 to June 2007, 65 patients underwent endovascular detachable coiling for 67 paraclinoid aneurysms (of which 9 were ruptured and 58 were unruptured) in our institute. Their medical records, radiological images and readings, and operation records were reviewed retrospectively.

RESULTS

After the initial embolization procedure, complete occlusion was achieved in 29 (43.3%) of the aneurysms treated by endovascular detachable coiling. Six aneurysms required retreatment, with two each requiring one, two, or three additional endovascular procedures. Fifty-five (82.1%) aneurysms were measured by three-dimensional time of flight (TOF) magnetic resonance images (MRI) or transfemoral cerebral angiography (TFCA) at a mean follow-up of 29.7 months (range from 4 to 94 months), with 39 aneurysms (70.9%) showing complete occlusion. Thromboembolic events (3.8%) were the most frequent complication. Rupture did not occur during or after any of the procedures. According to the Glasgow Outcome Scale (GOS), 98.4% of the patients treated by coil embolization had a score of 4 or 5.

CONCLUSION

Our results indicate that endovascular detachable coiling is a safe and effective treatment modality in paraclinoid aneurysms.

摘要

目的

即使是经验丰富的神经外科医生,对床突旁动脉瘤进行直接手术夹闭也面临技术挑战,这使得血管内治疗在许多中心成为一种替代治疗方式。因此,我们回顾性评估了床突旁动脉瘤血管内可脱性弹簧圈栓塞术的安全性和有效性。

方法

1997年6月至2007年6月,我院65例患者因67个床突旁动脉瘤接受了血管内可脱性弹簧圈栓塞术(其中9个为破裂动脉瘤,58个为未破裂动脉瘤)。对他们的病历、放射影像及解读结果以及手术记录进行了回顾性分析。

结果

在初次栓塞术后,血管内可脱性弹簧圈栓塞治疗的动脉瘤中有29个(43.3%)实现了完全闭塞。6个动脉瘤需要再次治疗,其中2个分别需要额外进行1次、2次或3次血管内操作。55个(82.1%)动脉瘤在平均29.7个月(4至94个月)的随访期内通过三维时间飞跃(TOF)磁共振成像(MRI)或经股动脉脑血管造影(TFCA)进行了测量,39个动脉瘤(70.9%)显示完全闭塞。血栓栓塞事件(3.8%)是最常见的并发症。在任何手术过程中或术后均未发生破裂。根据格拉斯哥预后量表(GOS),接受弹簧圈栓塞治疗的患者中有98.4%的评分为4分或5分。

结论

我们的结果表明,血管内可脱性弹簧圈栓塞术是治疗床突旁动脉瘤的一种安全有效的治疗方式。

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