Klossek J M, Peloquin L, Fourcroy P J, Ferrie J C, Fontanel J P
Department of Otolaryngology/Head and Neck Surgery, CHU Jean-Bernard, University of Poitiers, France.
Rhinology. 1996 Sep;34(3):179-83.
We report our experience with 10 cases of sphenoidal aspergillomas treated by endoscopic sinus surgery (ESS). Chronic symptoms such as cough, post-nasal discharge, dysphonia and even facial pain can be encountered in the history. Computerised tomography and, occasionally, magnetic resonance imaging are of great help in the assessment of this disease, especially when extensive skull base involvement is present. The radiological presentation can vary from an heterogeneous to homogeneous opacity with or without bone lysis to a frank pseudotumoural appearance. Four diagnostic tools have been evaluated to confirm the diagnosis: histology, direct smear, fungal cultures, and serology for Aspergillus. ESS has been successfully carried out without morbidity in all cases. No recurrence of the disease is seen after a mean follow-up of 27 months.
我们报告了10例经鼻内镜鼻窦手术（ESS）治疗的蝶窦曲霉菌瘤的经验。病史中可出现咳嗽、鼻后滴漏、声音嘶哑甚至面部疼痛等慢性症状。计算机断层扫描以及偶尔的磁共振成像对该病的评估有很大帮助，尤其是当存在广泛的颅底受累时。影像学表现可从不均匀到均匀的混浊，伴有或不伴有骨质溶解，到明显的假肿瘤外观。已评估了四种诊断工具以确诊：组织学、直接涂片、真菌培养和曲霉菌血清学检查。所有病例均成功进行了ESS，无并发症发生。平均随访27个月后未见疾病复发。
