Wine J J, Luckie D B
Cystic Fibrosis Research Laboratory, Stanford University, California 94305-2130, USA.
Curr Biol. 1996 Nov 1;6(11):1410-2. doi: 10.1016/s0960-9822(96)00744-0.
P-glycoprotein turns out not to be 'VSOAC', a known channel activated by cell swelling; it does seem to influence cell-volume recovery after swelling, but the physiological importance of this effect is presently unclear.
事实证明,P-糖蛋白并非“容积敏感性外向阴离子通道”(VSOAC),后者是一种已知的由细胞肿胀激活的通道;它似乎确实会影响肿胀后细胞容积的恢复,但这种效应的生理重要性目前尚不清楚。