蛋白质-蛋白质相互作用：PDZ结构域网络
Protein-protein interactions: PDZ domain networks.
作者信息
Fanning A S, Anderson J M
机构信息
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520-8019, USA.
出版信息
Curr Biol. 1996 Nov 1;6(11):1385-8. doi: 10.1016/s0960-9822(96)00737-3.
PMID:8939589
Abstract
PDZ domains can dimerize or bind to the carboxyl termini of unrelated proteins. Crystallographic studies demonstrate the structural basis for these interactions, which contribute to the ability of PDZ domains to create networks associated with the plasma membrane.
摘要
PDZ结构域可以二聚化或与不相关蛋白质的羧基末端结合。晶体学研究揭示了这些相互作用的结构基础，这些相互作用有助于PDZ结构域形成与质膜相关的网络。
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