Jones I, Morikawa Y
Institute of Virology, Mansfield Road, Oxford OX1 3SR, UK.
Curr Opin Biotechnol. 1996 Oct;7(5):512-6. doi: 10.1016/s0958-1669(96)80054-1.
Recombinant baculoviruses now represent a mature technology in which vector development, particularly for the control of expression level, has reached a plateau. However, other aspects of expression, such as the production of multiple proteins, improved product purification or maximizing protein processing, remain areas for novel vector and host cell development. This year has seen these topics come to the fore in descriptions of new expression systems.
重组杆状病毒如今代表了一项成熟的技术，其中载体开发，尤其是在表达水平控制方面，已达到一个平台期。然而，表达的其他方面，如多种蛋白质的生产、改进的产物纯化或蛋白质加工的最大化，仍然是新型载体和宿主细胞开发的领域。在对新表达系统的描述中，这些主题在今年已成为焦点。
