Huber O, Bierkamp C, Kemler R
Max-Planck Institute for Immunobiology, Department of Molecular Embryolog,y Stübeweg 51, D-79108 Freiburg, Germany.
Curr Opin Cell Biol. 1996 Oct;8(5):685-91. doi: 10.1016/s0955-0674(96)80110-4.
Cadherins and catenins represent key molecules during development. Recent findings demonstrate the involvement of cadherins and catenins in signaling pathways. In a working hypothesis, signaling via beta-catenin regulates the epithelial-mesenchymal transition in vertebrate development.
钙黏着蛋白和连环蛋白是发育过程中的关键分子。最近的研究结果表明钙黏着蛋白和连环蛋白参与了信号通路。在一个工作假说中,通过β-连环蛋白的信号传导调节脊椎动物发育过程中的上皮-间质转化。