天冬酰胺连接的糖基化对蛋白质结构和功能的调控
Modulation of protein structure and function by asparagine-linked glycosylation.
作者信息
O'Connor S E, Imperiali B
机构信息
Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
出版信息
Chem Biol. 1996 Oct;3(10):803-12. doi: 10.1016/s1074-5521(96)90064-2.
PMID:8939697
Abstract
In eukaryotic cells, many enzymes are devoted to the construction of the complex glycan structures that decorate secreted and cell-surface proteins. Recent studies have begun to elucidate the effects of asparagine-linked glycosylation on protein folding and on the structure and function of mature glycoproteins.
摘要
在真核细胞中，许多酶致力于构建修饰分泌蛋白和细胞表面蛋白的复杂聚糖结构。最近的研究已开始阐明天冬酰胺连接的糖基化对蛋白质折叠以及成熟糖蛋白的结构和功能的影响。
Zotero 插件