el-Ahl A A, Mashaly M M, Metwally M A
Chemistry Department, Faculty of Science at Mansoura, Egypt.
Boll Chim Farm. 1996 May;135(5):297-300.
3-Dicyanomethylideneindole derivatives were involved in (i) ring expansion reactions in alcoholic piperidine to form new quinolines from which a new pyridazinoquinoline was synthesised; and (ii) formation of new spiroindoloquinolines by reactions with cyclohexanone and beta-tetralone. The suggested structures of the new products were confirmed by IR, 1H-NMR, 13C-NMR and mass spectral analyses. Some of the new derivatives were active against the bacteria Escherichia cell.
3-二氰基亚甲基吲哚衍生物参与了：（i）在乙醇哌啶中进行扩环反应，以形成新的喹啉，进而合成了一种新的哒嗪并喹啉；（ii）与环己酮和β-四氢萘酮反应形成新的螺吲哚并喹啉。通过红外光谱、1H-核磁共振、13C-核磁共振和质谱分析证实了新产物的推测结构。一些新衍生物对大肠杆菌具有活性。
