Chrisomalis L, Baxi L V, Heller D
Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Am J Obstet Gynecol. 1996 Nov;175(5):1381-2. doi: 10.1016/s0002-9378(96)70062-5.
Chronic lymphocytic leukemia, a disease predominantly of elderly men, was incidentally diagnosed in a young pregnant patient. She did not require any chemotherapy and had a normal pregnancy outcome. However, she had repeated episodes of respiratory tract infections and anemia that required multiple antibiotics and transfusions. The placenta showed increased numbers of mature-appearing lymphocytes in the intervillous space, consistent with the diagnosis of chronic lymphocytic leukemia. To our knowledge this is the first reported case of chronic lymphocytic leukemia in pregnancy.